Views: 101 Author: Site Editor Publish Time: 2023-04-19 Origin: Site
Citicoline is a nucleic acid derivative. In 1956, Geiger found that citicoline could repair the brain injury in animal experiments. In 1957, Kennedy's research confirmed that it was crucial in the synthesis of brain phospholipids. In 1961, Takeda Pharmaceutical developed and produced the first product of citicoline-Nicholin. Now, citicoline is used in clinical medicine and mental health care products, which has a positive effect on the brain.
The accelerated pace of modern life has led to an increase in people's use of the brain, which has led to a great need not only for the elderly but also for young people to maintain attention and memory.
Citicoline sodium is a form of citicoline in practical applications, and it has been increasingly favored by groups that require high levels of focus and memory, such as athletes and students. Citicoline sodium is used as a nutritional supplement, which is rich in Choline and cytidine with neuroprotective activity. It can increasing norepinephrine(NE), acetylcholine(Ach), and dopamine levels nervous system by increasing the chemical in the brain called phosphatidylcholine. Phosphatidylcholine is necessary for proper brain functioning and sending messages to the brain.
Citicoline sodium is also currently the most popular drug for the treatment of brain diseases in the clinic, and plays an important role in the synthesis of lecithin. It can improve brain function by promoting the synthesis of lecithin. Experiments have proved that citicoline sodium can enhance the levels of norepinephrine and dopamine in the central nervous system, so as to treat cerebrovascular disease, brain injury and cognitive impairment caused by various reasons, without obvious side effects. It is mainly used to treat the sequelae of the nervous system caused by brain injury and cerebrovascular accident, and can be used for the treatment of Parkinson's disease, which has a certain effect on Alzheimer's disease.
Citicoline sodium is the safest natural intellectualizing substance for young and elderly people, with recommended doses ranging from 250mg to 1000mg per day. At present, citicoline sodium is mainly used as a health product in capsule form, while it can be used as a clinical drug in tablets, capsules, and injections. The citicoline sodium API is a white crystal or crystalline powder at room temperature.
Due to its high bioavailability and efficacy, citicoline sodium is very popular globally, with an annual demand for its API exceeding 500 tons. The main consumer markets are the United States, Europe, Southeast Asia, South America, North Africa, etc. In the US market, the main formulation manufacturers are JHD, NUTRILAND, and ROBINSON, they provide various clinical drug formulations or health products of citicoline sodium to meet the needs of different scenarios and populations. As the main source of raw materials for drugs in the world, China has many high-quality and stable manufacturers of citicoline sodium API, which provide over 70% of citicoline sodium raw materials to the world every year.
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